| February 1999 |
Dr. Ci:Labo Co., Ltd. was founded in Tokyo, starting with mail order sales of six skin-care products, including Aqua Collagen Gel. |
| March 2000 |
The company broke into the health food business. |
| December 2000 |
The company began selling ultrasonic beauty machines. |
| February 2001 |
The publication of the member's magazine, "Ci:Lover," was launched. |
| April 2001 |
The distribution center was set up in Kawaguchi City, Saitama-Prefecture. |
| May 2001 |
The company opened its first counseling type retail store in Nagoya's Meitetsu Department Store. |
| November 2001 |
The company started sales through online shops. |
| February 2002 |
Sales of the new brand Genomer began. |
| March 2003 |
The company became publicly listed on the JASDAQ stock market. |
| December 2003 |
Sales of the new brand Labo Labo began. |
| January 2004 |
First Hong Kong store was opened. |
| May 2004 |
First Hawaii store was opened. |
| October 2004 |
The company opened the Osaka sales office.
The company joined Nippon Keidanren. |
| December 2004 |
First Taiwan store was opened. |
| February 2005 |
The company listed on First Section of the Tokyo Stock Exchange. |
| December 2005 |
First North American store was opened. |
| March 2006 |
First South Korean store was opened.
The subsidiary Ci: investment Co., Ltd. was established.
The subsidiary MD science Co., Ltd. was established. |
| August 2006 |
The company's call center at Ebisu moved to Ikebukuro |
| April 2007 |
Sales of the new brand dr. brandt began. |
| January 2008 |
First Malaysian store was opened (by a distributor.) |